CDM
The "One Size Fits All" drugs model does not work:-
Managing the balance between optimal effect and acceptable toxity can be a challenging and arduous problem for physician and patient.
Cycle Dose Modifier (CDM) is a two-part mathematical process that changes the dose of a single or combination agent pharmacotherapy to attain a specific marker/s and concurrently manages the variables of Inter-Individual Variability. The bio-marker/s, are generally lab-values that are commonly used to assess the effect of the drug/s and includes markers of efficacy and toxicity. In the design of CDM while appreciating the complex nature of absorption, bioavailability, distribution, biotransformation, excretion and the kinetic processes we chose to directly link the cause (dose) to the effect (marker).
The product can be used:
- For any agent with biomarkers that are impacted by its dose
- In clinical practice by prescriber or patient:
- As a stand-alone instrument
- As part of an overall disease management system
- As a means to improve the pharmaceutical agent development process
- As part of the approved label (dose method) of a drug
- In single or multi-agent (combination) therapies