Biography

I've always been interested in medicine, mostly from the standpoint of trying to understand how things work. My educational and experience background is in emergency (field) medicine, nursing and I've been a Physician Assistant with specialty training in Oncology, Surgery and Internal Medicine for over forty years. Throughout my career I've had the opportunity to work in a variety of practices, locations and healthcare systems. As a person who recognizes problems and envisions solutions I generally feel comfortable disrupting the status quo to improve it. Years ago my Grandfather became ill with terminal cancer and I had to alter my work responsibilities to accommodate having him at home with my family as his life changed and ended. During that time I could afford day time nursing staff to care for him but night time premiums were too costly so I started a medical staff relief company sell my services to various doctors to cover their practice while they did something else, generally for a day or two but sometimes longer. During that time I worked for a surgeon who had developed quite a Family Practice and he asked me to join his practice.

I found that many of our patients had cardiovascular disorders and were being treated with a diuretic to reduce fluids but that fluid reduction stressed their kidneys in nearly two-thirds of these patients. I decided that I'd like to measure just how much fluid these patients had in their bodies because if their fluid wasn't expanded then reducing the fluid was what caused the change in kidney function. I visited area medical schools and university hospital and found that giving patients radioisotopes could be used to estimate their body water. However to measure it again the next day a different (new) isotope would have to be given. It seemed that getting the patients to submit to one isotope was challenging and to take a second to see how their body water had changed was asking too much. After further searching I found a Professor (emeritus) of cardiology at another area medical college, Dr. Jan Nyboer, MD, DSc who had successfully used a noninvasive electrical technique (impedance plethysmography) to estimate body water. I met and began to work with Dr. Nyboer and found the technique would noninvasively give water volume data and follow changes over time as I changed the diuretic doses given to patients with excess fluid and changed the patients without excess water to drugs better suited to treat their blood pressure and heart failure conditions. I purchased one of the instruments from the Company that built the original device and continued to use it in my practice. I was able to use it on all sorts of patients with all sorts of conditions in all sorts of practices areas, out-patient, in-patient, nursing homes, hospitals and critical care units.

Over time I found that the electrical measurements themselves with any conversion or manipulations gave the most helpful information about my patients. More-so one value; phase angle identified when patients were sickest (to pay more attention to them), when treatment worked best (to give better care) and when patients were going to die (to help make end-of-life plans).

Over time we have expanded our knowledge base in using the technology in any disease, any patient on any treatment. By working with professionals in other disciplines including pharmacotherapy, scientific design and management our team has been able to bring a product to market that can detect the presence, severity and progression of any disease, measure the effectiveness of treatment and identify the timing of non-acute death. More-so it tells us how are you doing, what is the cumulative effect of your life's activities, injuries, illnesses and what you have done (or not done) to recover and maintain your health (frailty). Prognosis and fluid status findings are used to significantly improve your care and outcome. We have issued United Sates patents that protect our method from any others using it. Most important, you can do the test and follow your results yourself.

Michaeal G. Singer, PA-C
John D. Kutzko, Pharm-D
Henry C. Lukaski, PhD
IPGDx, LLC.